Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6131224

O=[N+]([O-])c1ccc(-[n+]2ccccc2)c([N+](=O)[O-])c1.[Cl-]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.65
RAB9A P51151 1/20 0.65
ATM Q13315 1/20 0.65
TDP1 Q9NUW8 1/20 0.49
CYP1A2 P05177 2/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPK1 P28482 2/20 0.47
HIF1A Q16665 2/20 0.47
GPR35 Q9HC97 2/20 0.47
TSHR P16473 2/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TXNRD1 Q16881 1/20 0.46
TXNRD3 Q86VQ6 1/20 0.46
TXNRD2 Q9NNW7 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31173710 1.00 NPC1 (0.65) NPC1RAB9AATMTDP1CYP1A2
SCHEMBL741714 0.98 NPC1 (0.62) NPC1RAB9AATMTDP1CYP1A2
Hydrochloric Acid SCHEMBL10444520 0.97 NPC1 (0.61) NPC1RAB9AATMTDP1CYP1A2
Thiocyanic Acid SCHEMBL6501837 0.90 NPC1 (0.54) NPC1RAB9AATMTDP1CYP1A2
Hydrochloric Acid SCHEMBL8068701 0.88 NPC1 (0.67) NPC1RAB9AATMTDP1CYP1A2
SCHEMBL741713 0.87 NPC1 (0.51) NPC1RAB9AATMTDP1CYP1A2
Hydrochloric Acid SCHEMBL30343291 0.87 NPC1 (0.65) NPC1RAB9AATMTDP1CYP1A2
Hydrochloric Acid SCHEMBL599994 0.87 NPC1 (0.65) NPC1RAB9AATMTDP1CYP1A2
Hydrochloric Acid SCHEMBL10444521 0.86 NPC1 (0.50) NPC1RAB9AATMTDP1CYP1A2
SCHEMBL29618182 0.86 RAB9A (0.64) NPC1RAB9AATMTDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230100211-A1 PROCESS FOR THE PREPARATION OF SODIUM 4-(2-((1E,3E,5E,7Z)-7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO[e]INDOL-2(3H)-YLIDENE) HEPTA-1,3,5-TRIENYL)-1,1-DIMETHYL-1H-BENZO[e]INDOLIUM-3-YL) BUTANE-1-SULFONATE (INDOCYANINE GREEN) BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2023-03-30 US claimed
US-20190337896-A1 PROCESS FOR THE PREPARATION OF SODIUM 4-(2-((1E,3E,5E,7Z)-7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO[e]INDOL-2(3H)-YLIDENE) HEPTA-1,3,5-TRIENYL)-1,1-DIMETHYL-1H-BENZO[e]INDOLIUM-3-YL) BUTANE-1-SULFONATE (INDOCYANINE GREEN) BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2019-11-07 US claimed
EP-1015663-A1 CORROSION INHIBITION THROUGH THE USE OF A QUATERNARY PYRIDINE SALT-HYDROCARBON COMBINATION Stanchem Inc. (CA) 2000-07-05 EP claimed
WO-1998033953-A1 CORROSION INHIBITION THROUGH THE USE OF A QUATERNARY PYRIDINE SALT-HYDROCARBON COMBINATION STANCHEM INC. (CA) 1998-08-06 WO claimed
EP-0117196-B1 DERIVATIVES OF N-IMINOPYRIDINIUM BETAINES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS PROVESAN S.A. (CH) 1986-07-30 EP claimed
EP-4680678-A1 MECHANOCHEMICAL PROCESS FOR SYNTHESISING A CYANINE COMPOUND The University of Sussex (GB) 2026-01-21 EP disclosed
WO-2024189210-A1 MECHANOCHEMICAL PROCESS FOR SYNTHESISING A CYANINE COMPOUND THE UNIVERSITY OF SUSSEX (GB) 2024-09-19 WO disclosed
US-20230380264-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-11-23 US disclosed
US-11746426-B2 Stabilization of a co-bound intermediate via molecular tuning promotes CO2-to-ethylene conversion CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-09-05 US disclosed
US-20230100211-A1 PROCESS FOR THE PREPARATION OF SODIUM 4-(2-((1E,3E,5E,7Z)-7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO[e]INDOL-2(3H)-YLIDENE) HEPTA-1,3,5-TRIENYL)-1,1-DIMETHYL-1H-BENZO[e]INDOLIUM-3-YL) BUTANE-1-SULFONATE (INDOCYANINE GREEN) BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2023-03-30 US disclosed
EP-2905361-B1 METHOD OF FORMING A METAL COATING TOYOTA MOTOR CO LTD (JP) 2022-01-05 EP disclosed
WO-2021007508-A9 THE STABILIZATION OF A CO-BOUND INTERMEDIATE VIA MOLECULAR TUNING PROMOTES CO2-TO-ETHYLENE CONVERSION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2021-11-18 WO disclosed
US-4594312-A Photothermographic medium MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-06-10 US disclosed
US-4563467-A ANTIEDEMIC, LACTATION BLOCKERS PROVESAN S.A. (CH) 1986-01-07 US disclosed
EP-0120601-A2 Oxidative imaging MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-10-03 EP disclosed
EP-0119831-A2 Heat bleachable dye systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-09-26 EP disclosed
US-4218432-A Coloring agent and a composition including the same for coloring toilet bowl flushing water YAMAMOTO KAGAKU GOSEI CO., LTD. (JP) 1980-08-19 US disclosed
US-4088653-A FROM A CARBONYLHYDRAZIDE AND AN ARYL-PYRIDINIUM HALIDE, REDUCTION WITH A BOROHYDRIDE; ANALGESICS, ANTIINFLAMMATORY AND HYPERGLYCEMIC AGENTS CANADIAN PATENTS AND DEVELOPMENTS LIMITED (CA) 1978-05-09 US disclosed
US-4010156-A Process for the rearrangement of penicillins to cephalosporins and intermediate compounds thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-01 US disclosed
US-3932398-A 3-Halo-cepham derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337896-A1 PROCESS FOR THE PREPARATION OF SODIUM 4-(2-((1E,3E,5E,7Z)-7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO[e]INDOL-2(3H)-YLIDENE) HEPTA-1,3,5-TRIENYL)-1,1-DIMETHYL-1H-BENZO[e]INDOLIUM-3-YL) BUTANE-1-SULFONATE (INDOCYANINE GREEN) SULT1E1, IK, SULT1A1 NPC1 1516/4885RAB9A 1251/4885ATM 4613/4885
US-20230100211-A1 PROCESS FOR THE PREPARATION OF SODIUM 4-(2-((1E,3E,5E,7Z)-7-(1,1-DIMETHYL-3-(4-SULFONATOBUTYL)-1H-BENZO[e]INDOL-2(3H)-YLIDENE) HEPTA-1,3,5-TRIENYL)-1,1-DIMETHYL-1H-BENZO[e]INDOLIUM-3-YL) BUTANE-1-SULFONATE (INDOCYANINE GREEN) SULT1E1, IK, SULT1A1 NPC1 1516/4885RAB9A 1251/4885ATM 4613/4885
US-20230380264-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TIMCC, ICOSLG, NUDT1 NPC1 3889/4885RAB9A 3729/4885ATM 4237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.