SCHEMBL6131762

SCHEMBL6131762

Cc1ccccc1Nc1ccc(-c2ccc(Nc3ccccc3C)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 4/20 0.43
FABP3 P05413 3/20 0.40
GAA P10253 3/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
TP53 P04637 2/20 0.36
PKM P14618 1/20 0.36
PKLR P30613 1/20 0.36
PTGER4 P35408 1/20 0.36
SLC2A1 P11166 2/20 0.35
FABP5 Q01469 1/20 0.35
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPK10 P53779 1/20 0.35
MAPK13 O15264 1/20 0.35
MAPK12 P53778 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9408066 0.90 FABP4 (0.44) FABP4FABP3HPGDNPC1RAB9A
SCHEMBL29624616 0.90 FABP4 (0.49) FABP4FABP3GAAALDH1A1KDM4E
SCHEMBL6131761 0.85 HPGD (0.52) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL31265542 0.83 ALDH1A1 (0.45) GAAALDH1A1KDM4EHPGDPTGER4
SCHEMBL919587 0.83 MEN1 (0.39) GAAALDH1A1HPGDNPC1RAB9A
SCHEMBL3475626 0.82 FABP4 (0.45) FABP4FABP3GAAALDH1A1KDM4E
SCHEMBL7758598 0.82 HPGD (0.56) GAAALDH1A1KDM4EHPGDNPC1
SCHEMBL8417367 0.82 IDO1 (0.42) FABP4FABP3GAAALDH1A1NPC1
SCHEMBL8895701 0.82 RAB9A (0.41) FABP4FABP3GAAALDH1A1KDM4E
SCHEMBL8417151 0.82 PIK3CA (0.36) FABP4FABP3TP53FABP5MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0486038-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1996-10-16 EP claimed
EP-0486038-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-05-20 EP claimed
JP-62242950-A None JP disclosed
EP-1525629-A2 OPTOELECTRONIC DEVICES Qinetiq Limited (GB) 2005-04-27 EP disclosed
WO-2004013921-A2 OPTOELECTRONIC DEVICES QINETIQ LIMITED (GB) 2004-02-12 WO disclosed
EP-1186067-A1 CONDUCTING POLYMERS QinetiQ Limited (GB) 2002-03-13 EP disclosed
EP-0864932-B1 Image processing unit KYOCERA MITA CORP (JP) 2001-12-05 EP disclosed
EP-1147563-A1 ORGANIC LIGHT EMITTING MATERIAL AND DEVICE QinetiQ Limited (GB) 2001-10-24 EP disclosed
WO-2000070692-A1 CONDUCTING POLYMERS QINETIQ LIMITED (GB) 2000-11-23 WO disclosed
WO-2000035029-A1 ORGANIC LIGHT EMITTING MATERIAL AND DEVICE THE SECRETARY OF STATE FOR DEFENCE (GB) 2000-06-15 WO disclosed
US-5983056-A Photosensitive drum and image processing unit MITA INDUSTRIAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0864932-A1 Photosensitive drum and image processing unit MITA INDUSTRIAL CO., LTD. (JP) 1998-09-16 EP disclosed
EP-0411192-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1995-06-07 EP disclosed
EP-0411192-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-06 EP disclosed
JP-S62242950-A ELECTROPHOTOGRAPHIC SENSITIVE BODY FUJI XEROX CO LTD 1987-10-23 JP disclosed