SCHEMBL8417151

SCHEMBL8417151

CC(C)c1ccccc1Nc1ccc(-c2ccc(Nc3ccccc3C(C)C)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
PIK3CG P48736 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
EGFR P00533 1/20 0.34
FABP4 P15090 3/20 0.33
FABP3 P05413 2/20 0.33
RECQL P46063 1/20 0.33
FABP5 Q01469 1/20 0.33
CCR4 P51679 1/20 0.33
POLB P06746 1/20 0.33
TP53 P04637 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418920 0.87 HTT (0.35) L3MBTL1FABP4FABP3FABP5
SCHEMBL19773093 0.82 L3MBTL1 (0.44) PIK3CAPIK3CBPIK3CGL3MBTL1RECQL
SCHEMBL6131762 0.82 FABP4 (0.43) FABP4FABP3FABP5TP53MAPK13
SCHEMBL31265542 0.79 ALDH1A1 (0.45) L3MBTL1EGFRRECQL
SCHEMBL3475626 0.79 FABP4 (0.45) FABP4FABP3FABP5POLBMAPK14
SCHEMBL5686057 0.79 L3MBTL1 (0.47) PIK3CAPIK3CBPIK3CGL3MBTL1RECQL
SCHEMBL6131761 0.79 HPGD (0.52) EGFRPOLBTP53CA12CA2
SCHEMBL8417148 0.79 L3MBTL1 (0.39) PIK3CAPIK3CBPIK3CGL3MBTL1EGFR
SCHEMBL8417367 0.78 IDO1 (0.42) FABP4FABP3FABP5POLBMAPK13
SCHEMBL8895701 0.78 RAB9A (0.41) FABP4FABP3FABP5POLBMAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597128-B1 ESTER POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN CO (JP) 1999-09-15 EP disclosed
EP-0582722-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE FROM POLYCARBONATE POLYMER IDEMITSU KOSAN CO (JP) 1997-11-12 EP disclosed
EP-0411192-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1995-06-07 EP disclosed
EP-0597128-A1 ESTER POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-05-18 EP disclosed
EP-0582722-A1 POLYCARBONATE POLYMER, PRODUCTION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR MADE THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-02-16 EP disclosed
EP-0411192-A1 Electrophotographic photoreceptor IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-06 EP disclosed