Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 8/20 | 0.82 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.82 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131940 | 0.92 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6131986 | 0.85 | LMNA (0.60) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL6131787 | 0.85 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6131802 | 0.85 | ADRA1D (0.81) | ADRA1DADRA1AADRA1BKMT2AKDM4E | |
| SCHEMBL6131837 | 0.84 | ALDH1A1 (0.65) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL6131889 | 0.82 | ADRA1D (0.76) | ADRA1DADRA1AADRA1BKMT2AKDM4E | |
| SCHEMBL6132007 | 0.82 | ADRA1D (0.76) | ADRA1DADRA1AADRA1BKMT2AKDM4E | |
| SCHEMBL6131864 | 0.82 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BKMT2AKDM4E | |
| SCHEMBL6131810 | 0.82 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL6131853 | 0.81 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |