Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.70 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.70 |
| ▸ | HTR1A | P08908 | 3/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131773 | 0.92 | ADRA1D (0.82) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6131787 | 0.91 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6131986 | 0.91 | LMNA (0.60) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6131837 | 0.90 | ALDH1A1 (0.65) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL9720648 | 0.88 | HTR7 (0.70) | DRD2 | |
| SCHEMBL6131810 | 0.87 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL6131853 | 0.86 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL5442134 | 0.83 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6131794 | 0.83 | ADRA1D (0.68) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL1299348 | 0.81 | SIGMAR1 (0.79) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |