Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131972 | 0.86 | TMEM97 (0.56) | TMEM97KMT2ADRD2DRD3HTR3E | |
| Hydrochloric Acid SCHEMBL6132097 | 0.85 | TMEM97 (0.55) | TMEM97KDM4EALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6131880 | 0.84 | TMEM97 (0.55) | TMEM97KDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL6131773 | 0.82 | ADRA1D (0.82) | ADRA1DADRA1AADRA1BKMT2AKDM4E | |
| SCHEMBL6131873 | 0.80 | ALDH1A1 (0.53) | TMEM97KDM4EALDH1A1CYP2C19LMNA | |
| SCHEMBL7524534 | 0.78 | HTR1A (0.68) | ALDH1A1DRD2DRD3HTR3EHTR3B | |
| SCHEMBL255189 | 0.78 | HTR1A (0.68) | ALDH1A1DRD2DRD3HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL16528267 | 0.77 | MAPT (0.69) | ALDH1A1DRD2DRD3HTR3EHTR3B | |
| Bromide SCHEMBL10621563 | 0.77 | HTR1A (0.66) | ALDH1A1DRD2DRD3HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL787250 | 0.77 | MAPT (0.69) | ALDH1A1DRD2DRD3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |