Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131940 | 0.91 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6131787 | 0.88 | ADRA1D (0.59) | LMNAHTTADRA1DADRA1AADRA1B | |
| SCHEMBL6131837 | 0.87 | ALDH1A1 (0.65) | LMNAADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6131773 | 0.85 | ADRA1D (0.82) | ADRA1DADRA1AADRA1BHTR1AKDM4E | |
| SCHEMBL6131810 | 0.84 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6131937 | 0.84 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL6131853 | 0.84 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6131925 | 0.81 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BHTR1AKDM4E | |
| SCHEMBL6131928 | 0.81 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL6132097 | 0.80 | TMEM97 (0.55) | LMNAHTTHTR1ADRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |