Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6132097 | 0.88 | TMEM97 (0.55) | TMEM97ADRB1SIGMAR1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL6131880 | 0.87 | TMEM97 (0.55) | TMEM97ADRB1SIGMAR1HTR3EHTR3B | |
| SCHEMBL6131864 | 0.86 | ADRA1D (0.56) | TMEM97ADRB1SIGMAR1HTR3EHTR3B | |
| SCHEMBL6131787 | 0.81 | ADRA1D (0.59) | DRD2LMNA | |
| SCHEMBL6131873 | 0.81 | ALDH1A1 (0.53) | TMEM97CYP2C19LMNAMAPTSMN1; SMN2 | |
| Quipazine SCHEMBL6131841 | 0.79 | KDM4E (0.55) | TMEM97ADRB1SIGMAR1HTR3EHTR3B | |
| SCHEMBL30045575 | 0.75 | TAAR1 (0.73) | LMNAMAPTGAATAAR1TSHR | |
| SCHEMBL43681 | 0.75 | TAAR1 (0.73) | LMNAMAPTGAATAAR1TSHR | |
| SCHEMBL16978058 | 0.72 | TMEM97 (1.00) | TMEM97SIGMAR1KCNH2 | |
| Alcohol SCHEMBL7289118 | 0.71 | DRD2 (0.87) | ADRB1SIGMAR1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |