Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quipazine SCHEMBL6131841 | 0.83 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10TMEM97MAPK1 | |
| SCHEMBL6131854 | 0.82 | HTR1A (0.58) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL6131972 | 0.81 | TMEM97 (0.56) | TMEM97TSHRMAPK1LMNAMAPT | |
| SCHEMBL6131864 | 0.80 | ADRA1D (0.56) | ALDH1A1KDM4EHSD17B10TMEM97TSHR | |
| Hydrochloric Acid SCHEMBL6132097 | 0.80 | TMEM97 (0.55) | ALDH1A1KDM4ETMEM97TSHRMAPK1 | |
| SCHEMBL6131990 | 0.79 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL6131880 | 0.79 | TMEM97 (0.55) | ALDH1A1KDM4ETMEM97TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL6131775 | 0.78 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL30045575 | 0.74 | TAAR1 (0.73) | ALDH1A1KDM4ETSHRMAPK1LMNA | |
| SCHEMBL43681 | 0.74 | TAAR1 (0.73) | ALDH1A1KDM4ETSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |