Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137977 | 0.80 | AGER (0.54) | AGERL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL6137934 | 0.75 | SCN5A (0.49) | AGERL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL6137987 | 0.74 | L3MBTL1 (0.48) | AGERL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL6137702 | 0.67 | MEN1 (0.47) | L3MBTL1MAPTNPC1RAB9AGRIN2B | |
| Fenclonine SCHEMBL28422788 | 0.65 | SLC7A5 (0.79) | MAPTPPARGPPARAALPIPKM | |
| Fenclonine SCHEMBL8497239 | 0.65 | SLC7A5 (0.79) | MAPTPPARGPPARAALPIPKM | |
| SCHEMBL7332659 | 0.65 | BLM (0.42) | L3MBTL1MAPTGRIN2BPKMMEN1 | |
| SCHEMBL4133545 | 0.64 | EPHX1 (0.50) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL6137843 | 0.64 | TDP1 (0.45) | MAPTNPC1RAB9AGRIN2BKMT2A | |
| SCHEMBL6137828 | 0.64 | ACHE (0.56) | L3MBTL1NPC1RAB9AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032556-A4 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE INC (US) | 2005-02-02 | — | — | EP | claimed |
| EP-1032556-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999020599-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-04-29 | — | — | WO | claimed |