Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137702 | 0.85 | MEN1 (0.47) | L3MBTL1MAPTMEN1KMT2ATAS2R14 | |
| SCHEMBL6137934 | 0.82 | SCN5A (0.49) | AGERL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL6137828 | 0.82 | ACHE (0.56) | L3MBTL1MEN1KMT2ATAS2R14CXCR3 | |
| SCHEMBL6137987 | 0.81 | L3MBTL1 (0.48) | AGERL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL6137989 | 0.80 | AGER (0.42) | AGERL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL3058586 | 0.77 | GRIN2D (0.51) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3690613 | 0.77 | GRIN2D (0.58) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL27527274 | 0.76 | GRIN2D (0.54) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27675597 | 0.76 | HSD11B1 (0.50) | L3MBTL1MAPTMEN1KMT2APOLB | |
| SCHEMBL3454964 | 0.75 | AGER (0.56) | AGERL3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032556-A4 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE INC (US) | 2005-02-02 | — | — | EP | claimed |
| EP-1032556-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999020599-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-04-29 | — | — | WO | claimed |