Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 4/20 | 0.47 |
| ▸ | CTSG | P08311 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139016 | 1.00 | RGS4 (0.49) | RGS4GSK3AGSK3BMGLLELANE | |
| SCHEMBL907301 | 0.80 | RGS4 (0.64) | RGS4GSK3AGSK3BMGLLELANE | |
| SCHEMBL15131548 | 0.71 | RGS4 (0.66) | RGS4GSK3AGSK3BMGLLELANE | |
| SCHEMBL1133156 | 0.70 | MGLL (0.50) | RGS4GSK3AGSK3BMGLLELANE | |
| SCHEMBL2841938 | 0.69 | KMT2A (0.53) | RGS4GSK3AGSK3BMGLLELANE | |
| SCHEMBL9786685 | 0.68 | RGS4 (0.68) | RGS4GSK3AGSK3BMGLLELANE | |
| SCHEMBL10159006 | 0.68 | ELANE (0.62) | GSK3AGSK3BMGLLELANECTSG | |
| SCHEMBL168682 | 0.68 | RGS4 (0.49) | RGS4GSK3AGSK3BMGLLELANE | |
| SCHEMBL8133525 | 0.67 | ELANE (0.61) | RGS4GSK3AGSK3BMGLLELANE | |
| SCHEMBL24119845 | 0.67 | GSK3A (0.58) | RGS4GSK3AGSK3BMGLLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215772-A1 | Furanone derivatives and methods of making same | BIOSIGNAL LIMITED (AT) | 2005-09-29 | — | — | US | disclosed |
| EP-1539692-A4 | FURANONE DERIVATIVES AND METHODS OF MAKING SAME | BIOSIGNAL LTD (AU) | 2005-08-24 | — | — | EP | disclosed |
| EP-1539692-A1 | FURANONE DERIVATIVES AND METHODS OF MAKING SAME | Biosignal Limited (AU) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004016588-A1 | FURANONE DERIVATIVES AND METHODS OF MAKING SAME | BIOSIGNAL LIMITED (AU) | 2004-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215772-A1 | Furanone derivatives and methods of making same | PFAS, CFAP20, FDPS | RGS4 3777/4885GSK3A 2773/4885GSK3B 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.