Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 4/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067814 | 0.78 | CYP3A4 (0.42) | HSD17B2HSD17B1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5704971 | 0.78 | CASP1 (0.42) | SMN1; SMN2ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL6068082 | 0.78 | ESR2 (0.50) | HSD17B2HSD17B1ALDH1A1HPGDMAPT | |
| SCHEMBL22834010 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL23795185 | 0.75 | HSD17B1 (0.44) | HSD17B2HSD17B1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12182362 | 0.75 | HSD17B2 (0.44) | HSD17B2HSD17B1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5646084 | 0.73 | CA2 (0.55) | HSD17B2HSD17B1CA12CA2CA4 | |
| SCHEMBL5712508 | 0.72 | ALOX15 (0.41) | HSD17B2HSD17B1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9912150 | 0.71 | CYP2E1 (0.50) | ALDH1A1HSD17B10CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL22834155 | 0.71 | APP (0.75) | HSD17B2HSD17B1ALDH1A1HSD17B10ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495015-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | claimed |
| WO-2003087084-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | claimed |
| CN-106167502-A | Azetepa compound and preparation method thereof and the application as insecticide thereof | 广西师范学院 | 2016-11-30 | — | — | CN | disclosed |
| CN-106117268-A | α aminophosphonate compound with 2 amino 1,3,4 thiadiazoles structures and preparation method thereof and purposes | 广西师范学院 | 2016-11-16 | — | — | CN | disclosed |
| US-5328907-A | Treatment of allograft rejection in mammals and antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5108999-A | For treating inflammation, autoimmune disease or allograft rejection in mammals | SYNTEX (U.S.A.) INC. (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |
| US-5001124-A | 4-isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-03-19 | — | — | US | disclosed |