Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 1/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24099834 | 0.82 | VEGFA (0.49) | VEGFAEGLN1ALDH1A1KDM4EPKM | |
| SCHEMBL28566297 | 0.80 | VEGFA (0.65) | VEGFAEGLN1ALDH1A1KDM4EHTT | |
| SCHEMBL15094126 | 0.79 | KDM4E (0.53) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7758530 | 0.79 | GAA (0.57) | CYP2C19ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL8947821 | 0.79 | MEN1 (0.61) | CYP2C19ALDH1A1KDM4EHTTPKM | |
| SCHEMBL20137050 | 0.78 | VEGFA (0.54) | VEGFAEGLN1ALDH1A1KDM4EMEN1 | |
| SCHEMBL1713785 | 0.77 | ALDH1A1 (0.52) | VEGFAEGLN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL28576436 | 0.77 | VEGFA (0.75) | VEGFAEGLN1ALDH1A1KDM4EMEN1 | |
| SCHEMBL2936174 | 0.77 | ALDH1A1 (0.47) | VEGFAEGLN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL15302911 | 0.77 | VEGFA (0.46) | VEGFAEGLN1CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277746-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2005-05-11 | — | — | EP | disclosed |
| US-6686360-B2 | ANTIISCHEMIC AGENTS | LES LABORATOIRES SERVIER (FR) | 2004-02-03 | — | — | US | disclosed |
| US-20030158207-A1 | N-benzylpiperazine compounds | LES LABORATOIRES SERVIER (FR) | 2003-08-21 | — | — | US | disclosed |
| EP-1277746-A2 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions thereof | Les Laboratoires Servier (FR) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158207-A1 | N-benzylpiperazine compounds | NPPA, BAD, GLS | VEGFA 2640/4885EGLN1 582/4885CYP2C19 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.