SCHEMBL6140280

SCHEMBL6140280

C=CCc1cc(Cc2ccc(N)c(CC=C)c2)ccc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
GAA P10253 5/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 3/20 0.45
CYP3A4 P08684 2/20 0.45
POLB P06746 2/20 0.45
RAB9A P51151 1/20 0.45
ALDH1A1 P00352 5/20 0.41
CDC25B P30305 1/20 0.40
CASP6 P55212 1/20 0.40
RCE1 Q9Y256 1/20 0.40
XDH P47989 1/20 0.38
CYP1A2 P05177 1/20 0.38
GABRA1 P14867 6/20 0.38
GABRB2 P47870 6/20 0.38
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37
HPGD P15428 2/20 0.37
PPARG P37231 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599281 0.93 CYP3A4 (0.48) MAPTGAAMEN1KMT2AKDM4E
SCHEMBL1768780 0.90 XDH (0.48) MAPTGAAMEN1KMT2AKDM4E
SCHEMBL11129517 0.88 GABRA1 (0.36) MAPTGAAMEN1KMT2AKDM4E
SCHEMBL454406 0.81 GABRA1 (0.41) MAPTMEN1KMT2ACYP3A4POLB
SCHEMBL31290769 0.81 GABRA1 (0.41) MAPTMEN1KMT2ACYP3A4POLB
SCHEMBL5338575 0.79 GABRA1 (0.59) MAPTGAAMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL6307100 0.79 GABRA1 (0.39) MAPTGAAMEN1KMT2AKDM4E
SCHEMBL467130 0.77 DHFR (0.39) MAPTGAAMEN1KMT2AKDM4E
SCHEMBL240238 0.76 GABRA1 (0.66) MAPTGAAMEN1KMT2AKDM4E
SCHEMBL1269438 0.76 ALDH1A1 (0.45) POLBALDH1A1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573873-B1 Process for the preparation of urethane or urea groups-containing compact or cellular elastomers or mouldings thereof BASF AG (DE) 1997-12-29 EP claimed
EP-0438695-B1 Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-benzylurea groups, such elastomers and N-benzyl-polyoxyalkylene-polyamines suitable therefor BASF AG (DE) 1995-09-20 EP claimed
US-5364852-A Molding materials BASF AKTIENGESELLSCHAFT (DE) 1994-11-15 US claimed
EP-0438696-B1 Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-substituted urea- and amide groups, such elastomers and polyoxyalkylene-polyamine mixtures, containing polyazomethines, suitable therefor BASF AG (DE) 1994-11-02 EP claimed
EP-0573873-A2 Process for the preparation of urethane or urea groups-containing compact or cellular elastomers or mouldings thereof BASF Aktiengesellschaft (DE) 1993-12-15 EP claimed
EP-0284912-B1 Elastomers containing polyamide and polyurea groups and procedure for the preparation of elastic, compact or cellular mouldings thereof BASF AG (DE) 1993-11-24 EP claimed
US-5122547-A PRODUCTION OF ELASTIC, COMPACT OR CELLULAR MOLDINGS BASED ON ELASTOMERS CONTAINING N-BENZYLUREA GROUPS IN BOUND FORM, ELASTOMERS OF THIS TYPE, AND N-BENZYLPOLYOXYALKYLENE-POLYAMINES WHICH ARE SUITABLE FOR THIS PURPOSE BASF AKTIENGESELLSCHAFT (DE) 1992-06-16 US claimed
US-5084487-A Polyetherpolyimine copolymers for reaction injection molding BASF AKTIENGESELLSCHAFT (DE) 1992-01-28 US claimed
EP-0438696-A1 Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-substituted urea- and amide groups, such elastomers and polyoxyalkylene-polyamine mixtures, containing polyazomethines, suitable therefor BASF Aktiengesellschaft (DE) 1991-07-31 EP claimed
EP-0438695-A1 Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-benzylurea groups, such elastomers and N-benzyl-polyoxyalkylene-polyamines suitable therefor BASF Aktiengesellschaft (DE) 1991-07-31 EP claimed
US-4789691-A REACTING POLYISOCYANATE, POLYAZOMETHINE, AND AROMATIC POLYAMINES BASF AKTIENGESELLSCHAFT (DE) 1988-12-06 US claimed
US-11365281-B2 Coating composition and coating method KANSAI PAINT CO.. LTD. (JP) 2022-06-21 US disclosed
US-20200123306-A1 COATING COMPOSITION AND COATING METHOD KANSAI PAINT CO., LTD. (JP) 2020-04-23 US disclosed
EP-3337838-A1 PRODUCTION OF POLYURETHANE SOFT FOAMS WITH IMPROVED HARDNESS Evonik Degussa GmbH (DE) 2018-06-27 EP disclosed
US-8828548-B2 Interlayer adhesive, waterproof structure and waterproof construction method DYFLEX CORPORATION (JP) 2014-09-09 US disclosed
EP-1260548-B1 Plasticizer and urethane curable composition ASAHI GLASS CO LTD (JP) 2005-03-02 EP disclosed
US-20020198312-A1 Plasticizer and urethane curable composition ASAHI GLASS COMPANY, LIMITED (JP) 2002-12-26 US disclosed
EP-1260548-A1 Plasticizer and urethane curable composition ASAHI GLASS COMPANY LTD. (JP) 2002-11-27 EP disclosed
US-5077339-A Solid polyiscyanates, molten high molecular weight isocyanate-reactive compounds, and optionally chain extender or crosslinker BAYER AKTIENGESELLSCHAFT (DE) 1991-12-31 US disclosed
EP-0199086-A1 Curing agents in polyurethane manufacture UOP (US) 1986-10-29 EP disclosed