Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.48 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665328 | 0.82 | CHKA (0.55) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| SCHEMBL17982831 | 0.81 | ACHE (0.48) | KDM4EALDH1A1SMN1; SMN2POLBACHE | |
| Hydrochloric Acid SCHEMBL32665456 | 0.81 | CHKA (0.54) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| SCHEMBL32665181 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| SCHEMBL22791815 | 0.79 | ACHE (0.73) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| SCHEMBL4851304 | 0.78 | PKM (0.55) | KDM4EALDH1A1POLBACHEBACE1 | |
| SCHEMBL14058810 | 0.78 | LMNA (0.62) | KDM4EALDH1A1LMNAHPGDHDAC6 | |
| SCHEMBL24651197 | 0.77 | NR1H2 (0.64) | KDM4EALDH1A1POLBATM | |
| SCHEMBL2510658 | 0.77 | ALDH1A1 (0.70) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| SCHEMBL32665578 | 0.76 | TSHR (0.71) | KDM4EALDH1A1SMN1; SMN2POLBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515940-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-03-23 | — | — | EP | disclosed |
| EP-1506157-A2 | AMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097574-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |
| WO-2003097575-A2 | AMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |