Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.47 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141184 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| SCHEMBL32665328 | 0.80 | CHKA (0.55) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| Hydrochloric Acid SCHEMBL32665456 | 0.79 | CHKA (0.54) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| SCHEMBL32665221 | 0.78 | SOS1 (0.42) | ALDH1A1SMN1; SMN2MGLLFAAHHSP90AA1 | |
| SCHEMBL4851304 | 0.76 | PKM (0.55) | KDM4EALDH1A1POLBERAP1ATM | |
| SCHEMBL28797331 | 0.75 | MGLL (0.49) | KDM4EALDH1A1MGLLFAAHBACE1 | |
| SCHEMBL12658239 | 0.75 | LMNA (0.56) | KDM4EALDH1A1POLBHSP90AA1HSP90AB1 | |
| SCHEMBL2510658 | 0.75 | ALDH1A1 (0.70) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 | |
| SCHEMBL5072436 | 0.74 | MGLL (0.63) | KDM4EALDH1A1POLBMGLLFAAH | |
| SCHEMBL22791815 | 0.74 | ACHE (0.73) | KDM4EALDH1A1SMN1; SMN2POLBNR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | KDM4E 3880/4885ALDH1A1 3714/4885SMN1; SMN2 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.