SCHEMBL6141401

SCHEMBL6141401

CCCC[P+](CCCC)(CCCC)CC(F)(F)F.O=C([O-])c1cccc2[nH]nnc12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.31
RPS6KB1 P23443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238610 0.90 RIPK1 (0.35) RIPK1RPS6KB1
SCHEMBL1228378 0.89 RIPK1 (0.33) RIPK1RPS6KB1
SCHEMBL6565315 0.87 PARP1 (0.31)
SCHEMBL6140866 0.87 DNM1 (0.35) RIPK1RPS6KB1
SCHEMBL6141204 0.85 RIPK1 (0.34) RIPK1
SCHEMBL8165362 0.85 PARP1 (0.31)
SCHEMBL30848497 0.85 PARP1 (0.35) RIPK1RPS6KB1
SCHEMBL4780253 0.84 PRSS1 (0.34) RIPK1
SCHEMBL6141403 0.83 BDKRB2 (0.38)
Butyltriphenylphosphonium SCHEMBL6141574 0.81 ALDH1A1 (0.34) RIPK1RPS6KB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1090935-B1 FLUOROCOPOLYMER AND COMPOSITION THEREOF ASAHI GLASS CO LTD (JP) 2005-01-05 EP disclosed
US-6300446-B1 Fluorine-containing copolymer and composition thereof ASAHI GLASS COMPANY, LIMITED (JP) 2001-10-09 US disclosed
EP-1090935-A1 FLUOROCOPOLYMER AND COMPOSITION THEREOF ASAHI GLASS COMPANY LTD. (JP) 2001-04-11 EP disclosed