Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141204 | 0.95 | RIPK1 (0.34) | PRSS1PRSS2PRSS3RIPK1LTB4R | |
| SCHEMBL6140866 | 0.94 | DNM1 (0.35) | PRSS1PRSS2PRSS3RIPK1LTB4R | |
| SCHEMBL238610 | 0.91 | RIPK1 (0.35) | RIPK1LTB4RALOX5PARP1ALDH1A1 | |
| SCHEMBL6141547 | 0.90 | PARP1 (0.35) | PRSS1PRSS2PRSS3RIPK1LTB4R | |
| SCHEMBL6140803 | 0.88 | BDKRB2 (0.41) | PRSS1PRSS2PRSS3LTB4RBDKRB2 | |
| SCHEMBL1228378 | 0.87 | RIPK1 (0.33) | RIPK1ALOX5PARP1ALDH1A1CA2 | |
| SCHEMBL6141556 | 0.86 | ALDH1A1 (0.34) | PRSS1PRSS2PRSS3RIPK1LTB4R | |
| SCHEMBL6565315 | 0.86 | PARP1 (0.31) | PARP1 | |
| SCHEMBL30848497 | 0.85 | PARP1 (0.35) | RIPK1PARP1ALDH1A1CA2CYP3A4 | |
| SCHEMBL6141401 | 0.84 | RIPK1 (0.31) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180080585-A1 | FLUOROELASTOMER/EPDM HOSE FOR COLD-SIDE CHARGE AIR APPLICATIONS | CONTITECH MGW GMBH (DE) | 2018-03-22 | — | — | US | disclosed |
| WO-2018050586-A1 | FLUOROELASTOMER/EPDM HOSE FOR COLD-SIDE CHARGE AIR APPLICATIONS | CONTITECH MGW GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |
| EP-1669188-B1 | Hose construction containing NBR elastomer composition and fluoroplastic barrier | GOODYEAR TIRE & RUBBER (US) | 2008-03-12 | — | — | EP | disclosed |
| US-20060127619-A1 | Hose construction containing NBR elastomer composition and fluoroplastic barrier | THE GOODYEAR TIRE & RUBBER COMPANY | 2006-06-15 | — | — | US | disclosed |
| EP-1669188-A1 | Hose construction containing NBR elastomer composition and fluoroplastic barrier | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-06-14 | — | — | EP | disclosed |