SCHEMBL6141547

SCHEMBL6141547

CCCCCCCC[P+](C)(CCCCCCCC)CCCCCCCC.O=C([O-])c1cccc2[nH]nnc12

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 5/20 0.35
ALDH1A1 P00352 2/20 0.34
RIPK1 Q13546 1/20 0.33
LTB4R Q15722 3/20 0.33
ALOX5 P09917 2/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.32
RPS6KB1 P23443 1/20 0.32
SPHK2 Q9NRA0 1/20 0.31
SPHK1 Q9NYA1 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6141204 0.92 RIPK1 (0.34) PARP1ALDH1A1RIPK1LTB4RALOX5
SCHEMBL6140866 0.91 DNM1 (0.35) PARP1ALDH1A1RIPK1LTB4RALOX5
SCHEMBL4780253 0.90 PRSS1 (0.34) PARP1ALDH1A1RIPK1LTB4RALOX5
SCHEMBL238610 0.87 RIPK1 (0.35) PARP1ALDH1A1RIPK1LTB4RALOX5
SCHEMBL6141556 0.87 ALDH1A1 (0.34) ALDH1A1RIPK1LTB4RPRSS1PRSS2
SCHEMBL6140803 0.85 BDKRB2 (0.41) ALDH1A1LTB4RPRSS1PRSS2PRSS3
SCHEMBL10863252 0.84 RIPK1 (0.35) ALDH1A1RIPK1ALOX5TSHRLMNA
SCHEMBL1228378 0.84 RIPK1 (0.33) PARP1ALDH1A1RIPK1ALOX5RPS6KB1
SCHEMBL8165362 0.82 PARP1 (0.31) PARP1
SCHEMBL6565315 0.82 PARP1 (0.31) PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10266628-B2 Nitrile copolymer rubber composition ZEON CORPORATION (JP) 2019-04-23 US disclosed
US-9926445-B2 Nitrile copolymer rubber composition ZEON CORPORATION (JP) 2018-03-27 US disclosed
EP-2937382-B1 NITRILE COPOLYMER RUBBER COMPOSITION ZEON CORP (JP) 2017-10-25 EP disclosed
EP-2746330-B1 NITRILE COPOLYMER RUBBER COMPOSITION AND RUBBER CROSSLINK ZEON CORP (JP) 2017-07-19 EP disclosed
EP-2671914-B1 NITRILE RUBBER COMPOSITION, CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT ZEON CORP (JP) 2017-07-12 EP disclosed
US-20170101498-A1 NITRILE COPOLYMER RUBBER COMPOSITION ZEON CORPORATION (JP) 2017-04-13 US disclosed
EP-3124532-A1 NITRILE COPOLYMER RUBBER COMPOSITION Zeon Corporation (JP) 2017-02-01 EP disclosed
EP-2548919-B1 NITRILE COPOLYMER RUBBER COMPOSITION FOR HOSE AND CROSSLINKED MATERIAL ZEON CORP (JP) 2016-04-27 EP disclosed
EP-2463335-B1 NITRILE RUBBER COMPOSITION, CROSSLINKED NITRILE RUBBER COMPOSITION, CROSSLINKED RUBBER MATERIAL, AND METHOD FOR PRODUCING NITRILE RUBBER COMPOSITION ZEON CORP (JP) 2015-12-02 EP disclosed
US-20150322254-A1 NITRILE COPOLYMER RUBBER COMPOSITION ZEON CORPORATION (JP) 2015-11-12 US disclosed
US-20040038039-A1 Laminates of thermoplastic fluororesins and their manufacture ZEON CORPORATION (JP) 2004-02-26 US disclosed
EP-1332178-A1 LAMINATES OF THERMOPLASTIC FLUORORESINS AND THEIR MANUFACTURE Zeon Corporation (JP) 2003-08-06 EP disclosed
US-20030065067-A1 Crosslinkable elastic copolymer composition ASAHI GLASS COMPANY LIMITED (JP) 2003-04-03 US disclosed
US-6437028-B1 Crosslinkable elastic copolymer composition ASAHI GLASS COMPANY, LIMITED (JP) 2002-08-20 US disclosed
WO-2002038668-A1 LAMINATES OF THERMOPLASTIC FLUORORESINS AND THEIR MANUFACTURE ZEON CORPORATION (JP) 2002-05-16 WO disclosed
US-6300446-B1 Fluorine-containing copolymer and composition thereof ASAHI GLASS COMPANY, LIMITED (JP) 2001-10-09 US disclosed
EP-1130057-A1 CROSSLINKABLE ELASTIC COPOLYMER COMPOSITION ASAHI GLASS COMPANY LTD. (JP) 2001-09-05 EP disclosed
EP-1090935-A1 FLUOROCOPOLYMER AND COMPOSITION THEREOF ASAHI GLASS COMPANY LTD. (JP) 2001-04-11 EP disclosed
EP-0759354-B1 LAMINATE OF VULCANIZABLE RUBBER COMPOSITION LAYERS, PROCESS FOR PRODUCING A VULCANIZED RUBBER LAMINATE, AND RUBBER LAMINATE NIPPON ZEON CO (JP) 2000-08-16 EP disclosed
EP-0759354-A1 LAMINATE OF VULCANIZABLE RUBBER COMPOSITION LAYERS, PROCESS FOR PRODUCING RUBBER LAMINATE, AND RUBBER LAMINATE NIPPON ZEON CO., LTD. (JP) 1997-02-26 EP disclosed