Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FGR | P09769 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799881 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MAOAMAOBLMNA | |
| SCHEMBL25014 | 0.86 | HSD17B10 (0.50) | ALDH1A1HSD17B10MAOALMNAHTT | |
| SCHEMBL29546125 | 0.86 | HSD17B10 (0.50) | ALDH1A1HSD17B10MAOALMNAHTT | |
| SCHEMBL5703623 | 0.85 | MAOA (0.50) | ALDH1A1HSD17B10MAOAMAOBLMNA | |
| Water SCHEMBL27969596 | 0.83 | HSD17B10 (0.48) | ALDH1A1HSD17B10MAOALMNAHTT | |
| SCHEMBL904407 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HSD17B10MAOAMAOBLMNA | |
| SCHEMBL153531 | 0.83 | HSD17B10 (0.50) | ALDH1A1HSD17B10MAOAMAOBLMNA | |
| SCHEMBL31168188 | 0.83 | HSD17B10 (0.50) | ALDH1A1HSD17B10MAOAMAOBLMNA | |
| SCHEMBL3794847 | 0.83 | CYP3A4 (0.46) | ALDH1A1HSD17B10MAOAMAOBLMNA | |
| SCHEMBL5764832 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HSD17B10MAOALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3625210-B1 | SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2021-06-23 | — | — | EP | disclosed |
| US-10807084-B2 | Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines | COVESTRO DEUTSCHLAND AG (DE) | 2020-10-20 | — | — | US | disclosed |
| US-20200147594-A1 | SILICA-BASED ZINC CATALYSTS, THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES | COVESTRO DEUTSCHLAND AG (DE) | 2020-05-14 | — | — | US | disclosed |
| CN-110650944-A | Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines | 科思创德国股份有限公司 | 2020-01-03 | — | — | CN | disclosed |
| US-20120041207-A1 | Compound | STERIX LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| US-20110009448-A1 | Compound | STERIX LIMITED | 2011-01-13 | — | — | US | disclosed |
| US-7786152-B2 | Compound | STERIX LIMITED (GB) | 2010-08-31 | — | — | US | disclosed |
| US-20080114042-A1 | Inhibiting 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD); use of sulfonamide-substituted N-heterocyclics including pyrroles, oxazoles, thiazoles, imidazoles and their fused analogs to treat diabetes, obesity, hypertension, arthritis, asthma, osteoporosis, breast cancer | STERIX LIMITED (GB) | 2008-05-15 | — | — | US | disclosed |
| US-7309715-B2 | Compound | STERIX LIMITED (GB) | 2007-12-18 | — | — | US | disclosed |
| EP-1556040-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 AND TYPE 2 | Sterix Limited (GB) | 2005-07-27 | — | — | EP | disclosed |
| US-20040143124-A1 | Compound | STERIX LIMITED (GB) | 2004-07-22 | — | — | US | disclosed |
| WO-2004037251-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 AND TYPE 2 | STERIX LIMITED (GB) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147594-A1 | SILICA-BASED ZINC CATALYSTS, THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES | CDYL, ZYX, CXXC4 | ALDH1A1 4564/4885HSD17B10 3127/4885MAOA 421/4885 |
| US-20080114042-A1 | Inhibiting 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD); use of sulfonamide-substituted N-heterocyclics including pyrroles, oxazoles, thiazoles, imidazoles and their fused analogs to treat diabetes, obesity, hypertension, arthritis, asthma, osteoporosis, breast cancer | HSD11B1, HSD3B1, HSD11B2 | ALDH1A1 236/4885HSD17B10 33/4885MAOA 2529/4885 |
| US-10807084-B2 | Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines | CDYL, ZYX, CXXC4 | ALDH1A1 4564/4885HSD17B10 3127/4885MAOA 421/4885 |
| US-20110009448-A1 | Compound | NR4A1, GPR6, PRMT6 | ALDH1A1 1319/4885HSD17B10 1003/4885MAOA 1131/4885 |
| US-20120041207-A1 | Compound | NR4A1, GPR6, PRMT6 | ALDH1A1 1319/4885HSD17B10 1003/4885MAOA 1131/4885 |
| US-20040143124-A1 | Compound | NR4A1, CBR1, NR2C2 | ALDH1A1 553/4885HSD17B10 874/4885MAOA 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.