SCHEMBL6150757

SCHEMBL6150757

COc1cc(NC=O)c(C(=O)c2c(Cl)cccc2Cl)cc1OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.42
KDM4E B2RXH2 7/20 0.42
MAPT P10636 2/20 0.42
POLB P06746 2/20 0.41
LMNA P02545 1/20 0.41
CXCL12 P48061 1/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
GABRE P78334 1/20 0.41
GABRA6 Q16445 1/20 0.41
GABRG1 Q8N1C3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150594 0.77 CES2 (0.48) RORCKDM4ELMNACXCL12ALDH1A1
SCHEMBL6150107 0.77 KDM4E (0.54) RORCKDM4ELMNACXCL12GABRP
SCHEMBL27391515 0.75 ALDH1A1 (0.57) KDM4EMAPTPOLBLMNAALDH1A1
SCHEMBL28783724 0.74 KDM4E (0.45) KDM4EMAPTPOLBLMNAALDH1A1
SCHEMBL6307594 0.72 CES2 (0.46) RORCKDM4EMAPTLMNACXCL12
SCHEMBL6149592 0.72 LMNA (0.76) KDM4EMAPTPOLBLMNAALDH1A1
SCHEMBL6150742 0.71 CYP1A2 (0.68) MAPTPOLBLMNAALDH1A1PDE4D
SCHEMBL6150910 0.71 RORC (0.42) RORCKDM4ELMNACXCL12GABRP
SCHEMBL28285145 0.71 KDM4E (0.48) KDM4EMAPTALDH1A1MEN1CYP3A4
SCHEMBL28617698 0.71 HTT (0.47) KDM4EMAPTALDH1A1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727141-B1 Fungicidal methods, compounds and compositions containing benzophenones BASF AG (DE) 2005-11-02 EP disclosed
US-5922919-A Fungicidal methods, compounds and compositions containing benzophenones AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
US-5866722-A Fungicidal methods compounds and compositions containing benzophenones AMERICAN CYANAMID COMPANY (US) 1999-02-02 US disclosed
US-5773663-A FOR CONTROL OF PHYTOPATHOGENIC FUNGI IN CROPS AMERICAN CYANAMID COMPANY (US) 1998-06-30 US disclosed
US-5679866-A CONTROLLING POWDERY MELDEW DISEASES AMERICAN CYANAMID COMPANY (US) 1997-10-21 US disclosed
EP-0727141-A2 Fungicidal methods, compounds and compositions containing benzophenones American Cyanamid Company (US) 1996-08-21 EP disclosed