SCHEMBL6151172

SCHEMBL6151172

CC(CC(C)(C)C)c1ccccc1C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.44
HTT P42858 1/20 0.42
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
TSHR P16473 3/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.39
CHRM2 P08172 1/20 0.39
CYP3A4 P08684 1/20 0.39
ADRA2A P08913 1/20 0.39
OPRK1 P41145 1/20 0.39
HTR2B P41595 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27870313 0.88 BCAT2 (0.44) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL3380036 0.81 IRAK4 (0.47) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL1380696 0.81 TSHR (0.55) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL8526511 0.81 TSHR (0.55) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL3974925 0.79 IRAK4 (0.46) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL2848767 0.79 HTT (0.47) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL1003281 0.78 HTT (0.46) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL31632660 0.78 IRAK4 (0.55) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL105262 0.78 IRAK4 (0.55) IRAK4HTTALDH1A1KDM4EMAPT
SCHEMBL5918491 0.78 RIPK1 (0.43) ALDH1A1TSHRHPGDLMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599460-A2 OXATHIIN CARBOXAMIDE Bayer CropScience Aktiengesellschaft (DE) 2005-11-30 EP disclosed
WO-2004072023-A2 OXATHIIN CARBOXAMIDE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-08-26 WO disclosed