Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380036 | 0.84 | IRAK4 (0.47) | HTTIRAK4ALDH1A1TSHRMAPT | |
| SCHEMBL8526511 | 0.84 | TSHR (0.55) | HTTIRAK4ALDH1A1TSHRMAPT | |
| SCHEMBL1380696 | 0.84 | TSHR (0.55) | HTTIRAK4ALDH1A1TSHRMAPT | |
| SCHEMBL3974925 | 0.82 | IRAK4 (0.46) | HTTIRAK4ALDH1A1TSHRMAPT | |
| SCHEMBL1003281 | 0.81 | HTT (0.46) | HTTIRAK4ALDH1A1TSHRMAPT | |
| SCHEMBL31632660 | 0.81 | IRAK4 (0.55) | HTTIRAK4ALDH1A1TSHRMAPT | |
| SCHEMBL105262 | 0.81 | IRAK4 (0.55) | HTTIRAK4ALDH1A1TSHRMAPT | |
| SCHEMBL6151172 | 0.79 | IRAK4 (0.44) | HTTIRAK4ALDH1A1TSHRMAPT | |
| Acetic Acid SCHEMBL8193458 | 0.79 | BCAT2 (0.44) | HTTIRAK4ALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL28294057 | 0.79 | IRAK4 (0.53) | HTTIRAK4ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113346-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2023-04-13 | — | — | US | claimed |
| US-20150366201-A1 | FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-24 | — | — | US | claimed |
| US-20150181877-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-02 | — | — | US | claimed |
| US-20130217745-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-22 | — | — | US | claimed |
| EP-2229057-A1 | FUNGICIDAL COMPOSITIONS | Syngenta Participations AG (CH) | 2010-09-22 | — | — | EP | claimed |
| US-20100216640-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | claimed |
| EP-2150113-A1 | FUNGICIDAL COMPOSITIONS | Syngeta Participations AG (CH) | 2010-02-10 | — | — | EP | claimed |
| WO-2009090038-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-23 | — | — | WO | claimed |
| WO-2008131901-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-11-06 | — | — | WO | claimed |
| EP-1341757-B1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-20 | — | — | EP | claimed |
| US-7105565-B2 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-12 | — | — | US | claimed |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. | 2005-06-02 | — | — | US | claimed |
| EP-1341757-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | Syngenta Participations AG (CH) | 2003-09-10 | — | — | EP | claimed |
| WO-2002038542-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-16 | — | — | WO | claimed |
| US-11647749-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-16 | — | — | US | disclosed |
| US-20230113346-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2023-04-13 | — | — | US | disclosed |
| US-11570990-B2 | Fungicidal compositions comprising 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid methoxy-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-amide and an azole | SYNGENTA PARTICIPATIONS AG (CH) | 2023-02-07 | — | — | US | disclosed |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | SYNGENTA CROP PROTECTION, INC. | 2005-06-02 | — | — | US | disclosed |
| EP-1341757-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | Syngenta Participations AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002038542-A1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11647749-B2 | Fungicidal compositions | BROX, RER1, BLVRB | HTT 901/4885IRAK4 4400/4885ALDH1A1 2185/4885 |
| US-20150366201-A1 | FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE | CBR3, CBR1, C9 | HTT 405/4885IRAK4 4791/4885ALDH1A1 2067/4885 |
| US-20100216640-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | HTT 750/4885IRAK4 4461/4885ALDH1A1 2619/4885 |
| US-20150181877-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, ERG28, DPM1 | HTT 2063/4885IRAK4 4588/4885ALDH1A1 803/4885 |
| US-20050119130-A1 | Pyrrolcarboxamides and pyrrolcarbothioamides and their agrochemical uses | CBR3, PYCR1, CBR1 | HTT 3215/4885IRAK4 4102/4885ALDH1A1 3130/4885 |
| US-20230113346-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | HTT 901/4885IRAK4 4400/4885ALDH1A1 2185/4885 |
| US-20130217745-A1 | FUNGICIDAL COMPOSITIONS | CBR3, C1S, C9 | HTT 326/4885IRAK4 4865/4885ALDH1A1 2348/4885 |
| US-11570990-B2 | Fungicidal compositions comprising 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid methoxy-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-amide and an azole | CBR3, TH, CBR1 | HTT 786/4885IRAK4 4719/4885ALDH1A1 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.