Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585426 | 0.89 | HPGDS (0.33) | — | |
| SCHEMBL6152574 | 0.86 | SYK (0.35) | OPRM1 | |
| SCHEMBL6582104 | 0.84 | IDO1 (0.34) | — | |
| SCHEMBL6153355 | 0.81 | — | — | |
| SCHEMBL6581680 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL6581698 | 0.77 | ALDH1A1 (0.32) | OPRM1 | |
| SCHEMBL6579675 | 0.76 | TYMS (0.32) | OPRM1 | |
| SCHEMBL6291829 | 0.75 | JAK2 (0.40) | — | |
| SCHEMBL6152278 | 0.72 | ALDH1A1 (0.45) | — | |
| SCHEMBL6288883 | 0.70 | SLC26A6 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406610-B1 | USE OF SUBSTITUTED GAMMA-LACTONE COMPOUNDS AS MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2005-01-26 | — | — | EP | disclosed |