Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154733 | 0.82 | EPHX2 (0.57) | FAAH | |
| SCHEMBL6155218 | 0.80 | FAAH (0.56) | LMNAFAAHTSHRHPGD | |
| SCHEMBL6155721 | 0.78 | EPHX2 (0.46) | — | |
| SCHEMBL6154340 | 0.77 | CTSK (0.54) | TSHRHPGDALDH1A1MAPTRAB9A | |
| SCHEMBL27622738 | 0.76 | KMT2A (0.51) | LMNAALDH1A1RAB9A | |
| SCHEMBL10812443 | 0.76 | NPC1 (0.55) | LMNARAB9A | |
| SCHEMBL6154779 | 0.75 | FAAH (0.45) | LMNAFAAHHPGD | |
| SCHEMBL6155149 | 0.74 | LMNA (0.52) | LMNAFAAHALDH1A1MAPTMAPK1 | |
| SCHEMBL6153869 | 0.73 | CNR1 (0.55) | LMNAFAAHALDH1A1PKM | |
| SCHEMBL6157548 | 0.73 | FAAH (0.56) | CYP3A4LMNAFAAHTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |