Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.57 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593418 | 0.85 | SCN2A (0.60) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL6500304 | 0.83 | SCN2A (0.53) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL6153332 | 0.79 | AR (0.46) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL6154621 | 0.78 | LMNA (0.51) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL6005777 | 0.76 | SCN2A (0.72) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL10915309 | 0.76 | CYP3A4 (0.60) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL11307122 | 0.76 | CYP3A4 (0.56) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL8777039 | 0.74 | NR1H3 (0.53) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL29168849 | 0.74 | KMT2A (0.76) | SCN2ANR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL30758650 | 0.74 | KMT2A (0.76) | SCN2ANR1H3MEN1KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | SCN2A 789/4885NR1H3 147/4885MEN1 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.