Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 3/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156471 | 0.77 | JAK3 (0.40) | SLC6A4KCNH2SLC6A2SLC6A3MEN1 | |
| SCHEMBL27790242 | 0.74 | ALDH1A1 (0.44) | SLC6A4SLC6A2SLC6A3ALDH1A1MEN1 | |
| SCHEMBL83792 | 0.72 | SLC6A4 (0.47) | SLC6A4KCNH2SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL70661 | 0.71 | SLC6A4 (0.46) | SLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL25389337 | 0.71 | NOS2 (0.45) | SLC6A4KCNH2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL31283484 | 0.71 | NOS2 (0.45) | SLC6A4KCNH2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL6154711 | 0.70 | TOP2A (0.47) | TOP2AHSP90AB1PAK1 | |
| SCHEMBL15337010 | 0.70 | KMO (0.62) | — | |
| SCHEMBL2466000 | 0.69 | SLC6A4 (0.36) | SLC6A4KCNH2SLC6A2SLC6A3TOP2A | |
| SCHEMBL16670240 | 0.68 | SLC6A4 (0.41) | SLC6A4KCNH2SLC6A2ALDH1A1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | SLC6A4 712/4885KCNH2 118/4885SLC6A2 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.