SCHEMBL6155042

SCHEMBL6155042

CCCCOC(=O)CC(O)COS(=O)(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 2/20 0.39
PLA2G4B P0C869 1/20 0.39
MMP13 P45452 4/20 0.39
MMP3 P08254 1/20 0.39
ALDH1A1 P00352 4/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 2/20 0.39
KAT6A Q92794 1/20 0.38
MMP1 P03956 3/20 0.38
MMP7 P09237 3/20 0.38
MMP12 P39900 3/20 0.38
ACE P12821 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6157255 0.92 LMNA (0.41) MMP13ALDH1A1KAT6AMMP1MMP7
SCHEMBL6157724 0.87 HSD11B1 (0.44) TSHRMEN1KMT2AALDH1A1NPC1
SCHEMBL6155396 0.84 TSHR (0.39) TSHRTDP1L3MBTL1MEN1KMT2A
SCHEMBL6241318 0.83 RAB9A (0.45) TSHRTDP1MEN1KMT2AALDH1A1
SCHEMBL6153865 0.81 KCNA5 (0.40) TSHRPOLBRAB9ASMN1; SMN2
SCHEMBL8867929 0.81 TSHR (0.47) TSHRTDP1L3MBTL1MEN1KMT2A
SCHEMBL6242114 0.79 TSHR (0.45) TSHRMEN1KMT2AALDH1A1RAB9A
SCHEMBL6155099 0.79 MAPT (0.38) TSHRKMT2AALDH1A1RAB9A
SCHEMBL6155426 0.78 MAPT (0.40) TSHRL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL6153944 0.78 ABCB1 (0.41) TDP1MEN1KMT2AMMP13ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970947-B1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORP (JP) 2005-01-26 EP disclosed
US-6140527-A Process for producing butyric ester derivatives KANEKA CORPORATION (JP) 2000-10-31 US disclosed
EP-0970947-A1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORPORATION (JP) 2000-01-12 EP disclosed