SCHEMBL6155099

SCHEMBL6155099

CCC(C)OC(=O)CC(O)COS(=O)(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
ABCB1 P08183 3/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
ABCC1 P33527 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 1/20 0.33
HPGD P15428 1/20 0.33
HSD11B1 P28845 1/20 0.33
PSIP1 O75475 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6242114 0.88 TSHR (0.45) MAPTRAB9AALDH1A1GAAKMT2A
SCHEMBL6155437 0.84 ALDH1A1 (0.38) MAPTALDH1A1GAAKMT2AKDM4E
SCHEMBL6157724 0.83 HSD11B1 (0.44) RAB9ACHRM2CHRM1ALDH1A1GAA
SCHEMBL6238994 0.82 HPGD (0.42) MAPTALDH1A1GAAKMT2ATSHR
SCHEMBL6153865 0.82 KCNA5 (0.40) MAPTRAB9AGAAABCB1TSHR
SCHEMBL6241318 0.82 RAB9A (0.45) MAPTRAB9ACHRM2CHRM1ALDH1A1
SCHEMBL6157255 0.81 LMNA (0.41) CHRM2CHRM1ALDH1A1GAAHPGD
SCHEMBL28099707 0.80 PSIP1 (0.42) RAB9AALDH1A1GAATSHRHPGD
SCHEMBL6153944 0.79 ABCB1 (0.41) ALDH1A1KMT2AABCB1KDM4EHSD11B1
SCHEMBL6155388 0.79 MMP12 (0.41) MAPTALDH1A1GAAKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005005375-A1 METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS LANXESS DEUTSCHLAND GMBH (DE) 2005-01-20 WO claimed
EP-0970947-B1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORP (JP) 2005-01-26 EP disclosed
WO-2005005375-A1 METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS LANXESS DEUTSCHLAND GMBH (DE) 2005-01-20 WO disclosed
US-6140527-A Process for producing butyric ester derivatives KANEKA CORPORATION (JP) 2000-10-31 US disclosed
EP-0970947-A1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORPORATION (JP) 2000-01-12 EP disclosed