SCHEMBL6155396

SCHEMBL6155396

CCCCOC(=O)CC(O)COS(=O)(=O)c1ccccc1C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.37
ALDH1A1 P00352 4/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTGES O14684 1/20 0.35
ALOX5 P09917 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
LMNA P02545 1/20 0.35
PLA2G4B P0C869 1/20 0.34
ALOX15 P16050 1/20 0.34
ELANE P08246 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6157244 0.93 ALDH1A1 (0.36) MEN1KMT2APOLBALDH1A1CYP3A4
SCHEMBL6157266 0.89 ALDH1A1 (0.39) TSHRMEN1KMT2APOLBALDH1A1
SCHEMBL6155042 0.84 TSHR (0.41) TSHRL3MBTL1TDP1MEN1KMT2A
SCHEMBL6154454 0.83 POLB (0.41) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL6154515 0.81 POLB (0.37) MEN1KMT2APOLBALDH1A1MAPK1
SCHEMBL6155437 0.80 ALDH1A1 (0.38) MEN1KMT2APOLBALDH1A1
SCHEMBL6156140 0.80 CASP1 (0.43) L3MBTL1MEN1KMT2APOLBALDH1A1
SCHEMBL140993 0.79 KMT2A (0.43) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL6157255 0.77 LMNA (0.41) ALDH1A1TP53LMNA
SCHEMBL7060570 0.77 POLB (0.42) TSHRL3MBTL1TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970947-B1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORP (JP) 2005-01-26 EP disclosed
US-6140527-A Process for producing butyric ester derivatives KANEKA CORPORATION (JP) 2000-10-31 US disclosed
EP-0970947-A1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORPORATION (JP) 2000-01-12 EP disclosed