Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157255 | 0.89 | LMNA (0.41) | HSD11B1ALDH1A1CHRM2CHRM1ATM | |
| SCHEMBL6241318 | 0.88 | RAB9A (0.45) | TSHRALDH1A1CHRM2CHRM1NPC1 | |
| SCHEMBL6155042 | 0.87 | TSHR (0.41) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6153865 | 0.86 | KCNA5 (0.40) | TSHRRAB9ASMN1; SMN2GAA | |
| SCHEMBL6157266 | 0.84 | ALDH1A1 (0.39) | HSD11B1TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL6242114 | 0.83 | TSHR (0.45) | TSHRALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL6155099 | 0.83 | MAPT (0.38) | HSD11B1TSHRALDH1A1CHRM2CHRM1 | |
| SCHEMBL6153944 | 0.82 | ABCB1 (0.41) | HSD11B1ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL6155388 | 0.82 | MMP12 (0.41) | HSD11B1TSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6236220 | 0.81 | TSHR (0.42) | TSHRALDH1A1NPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005375-A1 | METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS | LANXESS DEUTSCHLAND GMBH (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-0970947-B1 | PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES | KANEKA CORP (JP) | 2005-01-26 | — | — | EP | disclosed |
| WO-2005005375-A1 | METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS | LANXESS DEUTSCHLAND GMBH (DE) | 2005-01-20 | — | — | WO | disclosed |
| US-6140527-A | Process for producing butyric ester derivatives | KANEKA CORPORATION (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0970947-A1 | PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES | KANEKA CORPORATION (JP) | 2000-01-12 | — | — | EP | disclosed |