Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250719 | 0.90 | CA2 (0.36) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1100608 | 0.83 | ALDH1A1 (0.36) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1070843 | 0.81 | HDAC1 (0.34) | TSHRALDH1A1 | |
| SCHEMBL1788899 | 0.80 | LMNA (0.35) | TSHR | |
| SCHEMBL1100758 | 0.79 | CA1 (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL9054275 | 0.79 | ALDH1A1 (0.44) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9586962 | 0.77 | NAAA (0.43) | TSHRALDH1A1 | |
| SCHEMBL5569443 | 0.77 | FAAH (0.34) | — | |
| SCHEMBL4339709 | 0.76 | NAAA (0.46) | TSHRALDH1A1 | |
| SCHEMBL198657 | 0.75 | CTSK (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357123-B1 | Novel carbapenem, medical and antibacterial comprisisng the same, and uses thereof | SUMITOMO PHARMA (JP) | 2005-11-30 | — | — | EP | disclosed |