SCHEMBL6155437

SCHEMBL6155437

CCC(C)OC(=O)CC(O)COS(=O)(=O)c1ccccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
POLB P06746 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
MEN1 O00255 2/20 0.33
ESR1 P03372 2/20 0.33
KMT2A Q03164 2/20 0.33
ESR2 Q92731 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ADRB2 P07550 2/20 0.32
ADRB1 P08588 2/20 0.32
ADRB3 P13945 2/20 0.32
ATM Q13315 1/20 0.32
CASP1 P29466 1/20 0.31
ALOX12 P18054 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6157266 0.85 ALDH1A1 (0.39) ALDH1A1NPSR1POLBCYP1A2CYP2C9
SCHEMBL6155099 0.84 MAPT (0.38) ALDH1A1NPSR1KMT2AGAAMAPT
SCHEMBL6154454 0.84 POLB (0.41) ALDH1A1SMN1; SMN2NPSR1POLBCYP1A2
SCHEMBL6157244 0.82 ALDH1A1 (0.36) ALDH1A1NPSR1POLBCYP1A2CYP2C9
SCHEMBL6154515 0.81 POLB (0.37) ALDH1A1NPSR1POLBCYP1A2CYP2C9
SCHEMBL6156140 0.81 CASP1 (0.43) ALDH1A1SMN1; SMN2NPSR1POLBCYP1A2
SCHEMBL140993 0.80 KMT2A (0.43) ALDH1A1SMN1; SMN2POLBCYP1A2CYP2C9
SCHEMBL6155396 0.80 TSHR (0.39) ALDH1A1POLBMEN1KMT2A
SCHEMBL6238994 0.80 HPGD (0.42) ALDH1A1KMT2AGAAMAPT
SCHEMBL28060735 0.76 CYP1A2 (0.51) ALDH1A1POLBCYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970947-B1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORP (JP) 2005-01-26 EP disclosed
US-6140527-A Process for producing butyric ester derivatives KANEKA CORPORATION (JP) 2000-10-31 US disclosed
EP-0970947-A1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORPORATION (JP) 2000-01-12 EP disclosed