Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27634513 | 0.85 | ACHE (0.40) | ACHEL3MBTL1POLBNAMPTALDH1A1 | |
| SCHEMBL6155749 | 0.85 | ACHE (0.40) | ACHEL3MBTL1POLBNAMPTHTT | |
| SCHEMBL2076282 | 0.83 | ACHE (0.39) | ACHEL3MBTL1POLBPARP1IRAK4 | |
| SCHEMBL31226879 | 0.83 | ACHE (0.41) | ACHEL3MBTL1POLBPARP1IRAK4 | |
| SCHEMBL952140 | 0.81 | L3MBTL1 (0.50) | L3MBTL1POLBNAMPTHTTJAK3 | |
| SCHEMBL6156337 | 0.81 | ALDH1A1 (0.43) | ACHEL3MBTL1POLBNAMPTALDH1A1 | |
| SCHEMBL6154440 | 0.80 | TSHR (0.42) | L3MBTL1ALDH1A1 | |
| SCHEMBL26419226 | 0.75 | ADORA3 (0.39) | L3MBTL1PARP1NAMPTNNMTJAK2 | |
| SCHEMBL1224892 | 0.74 | GAA (0.50) | POLBNAMPTNNMTALDH1A1 | |
| SCHEMBL26406052 | 0.74 | ADORA3 (0.38) | L3MBTL1PARP1PDK2NAMPTNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |