Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17437947 | 0.87 | TSHR (0.42) | TSHRALDH1A1MAPTCA12CA1 | |
| SCHEMBL6156337 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL27086400 | 0.85 | TSHR (0.40) | TSHRALDH1A1MAPTNR1H2CA12 | |
| SCHEMBL23273647 | 0.84 | L3MBTL1 (0.47) | TSHRALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL2089856 | 0.82 | KDM4E (0.46) | TSHRALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL6155749 | 0.81 | ACHE (0.40) | ALDH1A1SMN1; SMN2L3MBTL1HSD17B10GAA | |
| SCHEMBL27634513 | 0.81 | ACHE (0.40) | TSHRALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL6971478 | 0.80 | ACHE (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL573457 | 0.78 | ADORA3 (0.51) | TSHRALDH1A1MAPTNR1H2KDM4E | |
| SCHEMBL3267578 | 0.77 | TSHR (0.50) | TSHRALDH1A1MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |