Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155897 | 0.78 | PPARA (0.45) | PPARAKMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL6157345 | 0.76 | MAOB (0.43) | KMT2AALDH1A1MEN1MAPTMAOB | |
| SCHEMBL2781564 | 0.75 | PPARA (0.35) | PPARAKMT2AL3MBTL1 | |
| SCHEMBL10687046 | 0.73 | PPARA (0.62) | PPARAKMT2AL3MBTL1ALDH1A1RXRA | |
| SCHEMBL10690742 | 0.72 | PPARA (0.61) | PPARAKMT2AL3MBTL1ALDH1A1RXRA | |
| SCHEMBL3689203 | 0.72 | MTNR1A (0.43) | KMT2AL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL22658227 | 0.71 | CRHBP (0.68) | KMT2AL3MBTL1ALDH1A1MEN1TSHR | |
| SCHEMBL334924 | 0.70 | KDM4E (0.56) | KMT2AL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL10442102 | 0.70 | ALDH1A1 (0.47) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL6155995 | 0.70 | PPARA (0.41) | PPARAKMT2AL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |