Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155143 | 0.85 | NAAA (0.40) | TRPV1LMNAMAPTNFKB1NFKB2 | |
| SCHEMBL27701669 | 0.78 | CHRNB2 (0.47) | NPC1SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL27704256 | 0.77 | NOTUM (0.48) | TRPV1LMNANOTUMMAPTL3MBTL1 | |
| SCHEMBL6154334 | 0.77 | ALDH1A1 (0.39) | LMNANPC1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL28359033 | 0.76 | LMNA (0.64) | LMNAPOLBMAPTNFKB1NFKB2 | |
| SCHEMBL26957589 | 0.75 | NOTUM (0.51) | TRPV1LMNANOTUML3MBTL1SMN1; SMN2 | |
| SCHEMBL27921411 | 0.74 | NOTUM (0.58) | TRPV1LMNANOTUMMAPTL3MBTL1 | |
| SCHEMBL6157034 | 0.73 | TDP1 (0.54) | TRPV1LMNAPOLBL3MBTL1TDP1 | |
| SCHEMBL28914950 | 0.72 | LMNA (0.62) | LMNAPOLBMAPTNFKB1NFKB2 | |
| SCHEMBL6157548 | 0.72 | FAAH (0.56) | TRPV1LMNAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |