Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155143 | 0.78 | NAAA (0.40) | ALDH1A1HDAC3HDAC1HDAC2CYP1A2 | |
| SCHEMBL9124901 | 0.78 | PRSS1 (0.35) | PRSS1PRSS2PRSS3 | |
| SCHEMBL25081069 | 0.77 | LIPE (0.47) | LIPECYP2C19POLQLMNAHTT | |
| SCHEMBL6157543 | 0.77 | TRPV1 (0.53) | ALDH1A1CYP1A2CYP2C19LMNAHTT | |
| SCHEMBL28770588 | 0.75 | KDM4E (0.47) | ALDH1A1ALOX12PRSS1PRSS2PRSS3 | |
| SCHEMBL761922 | 0.75 | ALOX15 (0.45) | ALDH1A1LIPEHDAC3HDAC4HDAC1 | |
| SCHEMBL6154861 | 0.74 | TLR2 (0.45) | ALDH1A1ALOX12PRSS1PRSS2PRSS3 | |
| SCHEMBL16415718 | 0.74 | LMNA (0.47) | ALDH1A1LIPECYP2C19POLQKDM4E | |
| SCHEMBL27701669 | 0.74 | CHRNB2 (0.47) | ALDH1A1PRSS1PRSS2PRSS3NPC1 | |
| SCHEMBL31403308 | 0.73 | PRSS1 (0.37) | ALDH1A1ALOX12PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | claimed |
| EP-1499326-A1 | OXOLIDE ANTIBACTERIALS | Abbott Laboratories (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003090760-A1 | OXOLIDE ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2003-11-06 | — | — | WO | disclosed |