Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171198 | 0.81 | DRD2 (0.71) | ALDH1A1TSHRSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL6159875 | 0.80 | HTR2A (0.54) | HTR2AHTR2CSLC6A4SLC6A3HTR1A | |
| SCHEMBL11123253 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL6162560 | 0.75 | DRD2 (0.45) | SMN1; SMN2MAPTHTR1AGAADRD2 | |
| SCHEMBL25819265 | 0.74 | GAA (0.57) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL6162708 | 0.73 | L3MBTL1 (0.55) | ALDH1A1KDM4ESMN1; SMN2HPGDGAA | |
| SCHEMBL3436300 | 0.73 | DRD2 (0.49) | ALDH1A1HTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL8218392 | 0.72 | HTR1A (0.67) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL4875267 | 0.72 | ALDH1A1 (0.79) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL7775626 | 0.72 | HTR1A (0.77) | ALDH1A1KDM4EHTTTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |