Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.45 |
| ▸ | DRD4 | P21917 | 10/20 | 0.45 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159481 | 0.80 | OPRL1 (0.44) | DRD4PARK7HSD11B1 | |
| SCHEMBL6159469 | 0.75 | ALDH1A1 (0.51) | DRD2DRD4DRD3GAASMN1; SMN2 | |
| SCHEMBL8222205 | 0.74 | MAPK1 (0.43) | DRD2DRD4PARK7DRD3GAA | |
| SCHEMBL6162708 | 0.73 | L3MBTL1 (0.55) | GAALMNASMN1; SMN2 | |
| SCHEMBL8219466 | 0.72 | GAA (0.47) | DRD2DRD4DRD3GAAHTR1A | |
| SCHEMBL6160264 | 0.71 | MAPT (0.45) | DRD2DRD4DRD3GAALMNA | |
| SCHEMBL6160253 | 0.71 | MAPT (0.45) | DRD2DRD4DRD3GAALMNA | |
| SCHEMBL6162084 | 0.69 | HTR1A (0.57) | GAALMNASMN1; SMN2HTR1AHTR7 | |
| SCHEMBL6161129 | 0.69 | HTR1A (0.52) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL19562130 | 0.68 | SLC6A4 (0.52) | DRD4GAAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |