SCHEMBL197689

SCHEMBL197689

CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.44
CTSK P43235 3/20 0.44
CTSS P25774 2/20 0.44
CTSL P07711 2/20 0.43
CTSB P07858 1/20 0.43
TRPA1 O75762 2/20 0.41
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
ELANE P08246 1/20 0.38
KLK5 Q9Y337 1/20 0.38
CYP2D6 P10635 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SRC P12931 1/20 0.36
PSENEN Q9NZ42 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7061312 1.00 PREP (0.44) PREPCTSKCTSSCTSLCTSB
SCHEMBL6159871 1.00 PREP (0.44) PREPCTSKCTSSCTSLCTSB
SCHEMBL29484188 0.95 CTSK (0.46) PREPCTSKCTSSCTSLCTSB
SCHEMBL2580872 0.93 PREP (0.39) PREPCTSKCTSSCTSLCTSB
SCHEMBL721602 0.90 PREP (0.38) PREPCTSKCTSSCTSLCTSB
SCHEMBL31587441 0.89 CTSK (0.45) PREPCTSKCTSSCTSLCTSB
SCHEMBL11803999 0.87 CTSK (0.38) PREPCTSKCTSSCTSLCTSB
SCHEMBL4969025 0.87 CTSK (0.49) CTSKCTSSCTSLCTSBCA2
SCHEMBL5696168 0.87 CTSK (0.49) CTSKCTSSCTSLCTSBCA2
SCHEMBL23771884 0.86 CTSK (0.38) PREPCTSKCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637441-B2 Prodrugs of the tyrosine kinase inhibitor for treating cancer Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-05-26 US disclosed
WO-2026090173-A1 MODIFIED SELF-IMMOLATING MOIETIES IN ANTIBODY-DRUG CONJUGATES CODEABLE THERAPEUTICS, INCORPORATED (US) 2026-04-30 WO disclosed
WO-2026085848-A1 NANO-DRUG DELIVERY SYSTEM MODIFIED WITH PHENOLIC ACID OR DIPEPTIDE FOR INCREASING ORAL ABSORBABILITY AND BIOAVAILABILITY, AND USE THEREOF 四川大学 2026-04-30 WO disclosed
US-12612420-B2 Arginase inhibitors and methods of use thereof MOLECURE S.A. (PL) 2026-04-28 US disclosed
EP-4725560-A2 ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS Bayer Pharma Aktiengesellschaft (DE) 2026-04-15 EP disclosed
US-20260098013-A1 Stereoisomer Conjugates of Dextrorphan ZEVRA THERAPEUTICS INC (US) 2026-04-09 US disclosed
EP-3810615-B1 ARGINASE INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2026-01-28 EP disclosed
EP-4673474-A2 ANTI-PSMA ANTIBODIES, CONJUGATES, AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2026-01-07 EP disclosed
US-20250320233-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO LTD (KR) 2025-10-16 US disclosed
EP-4619037-A1 SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT Lerchen, Hans-Georg (DE) 2025-09-24 EP disclosed
EP-0654041-B1 PEPTIDYL 4-AMINO-2,2-DIFLUORO-3-OXO-1,6-HEXANEDIOIC ACID DERIVATIVES AS ANTIINFLAMMATORY AGENTS PFIZER (US) 1998-07-01 EP disclosed
EP-0838471-A1 PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST SAGAMI CHEMICAL RESEARCH CENTER (JP) 1998-04-29 EP disclosed
US-5739279-A Peptidyl 4-amino-2,2-difluoro-3-oxo-1,6-hexanedioic acid derivatives as antiinflammatory agents PFIZER INC. (US) 1998-04-14 US disclosed
EP-0761678-A1 Fluorine-containing anthracycline derivatives having hydroxyl group(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1997-03-12 EP disclosed
EP-0632808-A1 ANTIVIRAL PEPTIDES Pfizer Limited (GB) 1995-01-11 EP disclosed
WO-1993023373-A1 N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS PFIZER LIMITED (GB) 1993-11-25 WO disclosed
EP-0569598-A1 BENZOXAZINONE DERIVATIVE JAPAN TOBACCO INC. (JP) 1993-11-18 EP disclosed
WO-1993019059-A1 ANTIVIRAL PEPTIDES PFIZER LIMITED (GB) 1993-09-30 WO disclosed
EP-0337714-A2 HIV protease inhibitors useful for the treatment of aids MERCK & CO. INC. (US) 1989-10-18 EP disclosed
US-4237047-A FLUORESCENT SUBSTRATE FOR MEASURING ENZYME ACTIVITY AJINOMOTO COMPANY, INCORPORATED (JP) 1980-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320233-A1 ARGINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ARG1, ARG2, PRMT1 PREP 867/4885CTSK 1677/4885CTSS 1500/4885
US-12637441-B2 Prodrugs of the tyrosine kinase inhibitor for treating cancer EGFR, ERBB2, MET PREP 2966/4885CTSK 595/4885CTSS 977/4885
US-12612420-B2 Arginase inhibitors and methods of use thereof ARG1, ARG2, ARGLU1 PREP 86/4885CTSK 1074/4885CTSS 628/4885
US-20260098013-A1 Stereoisomer Conjugates of Dextrorphan OPRM1, OPRD1, OPRK1 PREP 2459/4885CTSK 4223/4885CTSS 3646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.