Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30277953 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP2A6MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL774076 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP2A6MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL443271 | 0.78 | CYP1A2 (0.57) | CYP1A2CYP2A6MTNR1AMTNR1BACHE | |
| SCHEMBL5510892 | 0.78 | CYP1A2 (0.59) | CYP1A2CYP2A6MTNR1AMTNR1BACHE | |
| SCHEMBL29869216 | 0.78 | CYP1A2 (0.57) | CYP1A2CYP2A6MTNR1AMTNR1BACHE | |
| SCHEMBL7514393 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP2A6MTNR1AMTNR1BACHE | |
| SCHEMBL1806697 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP2A6MTNR1AMTNR1BACHE | |
| SCHEMBL1806698 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP2A6MTNR1AMTNR1BACHE | |
| SCHEMBL9709432 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP2A6MTNR1AMTNR1BACHE | |
| SCHEMBL8749346 | 0.77 | CYP1A2 (0.55) | CYP1A2CYP2A6MTNR1AMTNR1BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981152-B2 | Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-03-17 | — | — | US | disclosed |
| US-20140197024-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-07-17 | — | — | US | disclosed |
| US-8779200-B2 | Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-07-15 | — | — | US | disclosed |
| US-20120041234-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETIES ACT (ACT XXI OF 1860)) (IN) | 2012-02-16 | — | — | US | disclosed |
| WO-2010097811-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | disclosed |
| US-4144397-A | Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed magnesium halide complex | SYNTEX CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140197024-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | WFS1, EPHX2, MANBA | CYP1A2 155/4885CYP2A6 320/4885MTNR1A 3570/4885 |
| US-20120041234-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | AADAC, NAT1, CTRB1 | CYP1A2 291/4885CYP2A6 97/4885MTNR1A 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.