Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077208 | 0.90 | FNTA (0.47) | ALDH1A1DRD3DRD2OPRL1PTAFR | |
| SCHEMBL6482895 | 0.89 | FNTA (0.47) | ALDH1A1DRD3DRD2OPRL1PTAFR | |
| SCHEMBL3088918 | 0.89 | LMNA (0.46) | ALDH1A1TBXAS1ACHEPTAFRLMNA | |
| SCHEMBL6268837 | 0.86 | ACHE (0.46) | ALDH1A1TBXAS1DRD3DRD2ACHE | |
| SCHEMBL6777801 | 0.81 | LMNA (0.43) | ALDH1A1TBXAS1ACHEPTAFRLMNA | |
| SCHEMBL6271049 | 0.77 | OPRL1 (0.46) | ALDH1A1DRD3DRD2OPRL1PTAFR | |
| SCHEMBL7672874 | 0.77 | CHRNA7 (0.57) | ALDH1A1DRD3DRD2PTAFRHTR1A | |
| SCHEMBL3458409 | 0.75 | ALDH1A1 (0.63) | ALDH1A1DRD3DRD2PTAFRHTR1A | |
| SCHEMBL87991 | 0.74 | LMNA (0.49) | ALDH1A1PTAFRLMNACYP1A2CYP3A4 | |
| SCHEMBL3074297 | 0.74 | TBXAS1 (0.35) | TBXAS1DRD3HTR1AHTR2AFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060163-B1 | NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | KLINGE CO CHEM PHARM FAB (DE) | 2005-10-12 | — | — | EP | claimed |