Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 3/20 | 0.39 |
| ▸ | PTAFR | P25105 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088918 | 0.86 | LMNA (0.46) | LMNAALDH1A1TBXAS1C3AR1PTAFR | |
| SCHEMBL6163043 | 0.81 | ALDH1A1 (0.43) | LMNAALDH1A1TBXAS1C3AR1PTAFR | |
| SCHEMBL6268837 | 0.78 | ACHE (0.46) | LMNAALDH1A1TBXAS1C3AR1PTAFR | |
| SCHEMBL87991 | 0.72 | LMNA (0.49) | LMNAALDH1A1C3AR1PTAFRCYP1A2 | |
| SCHEMBL3077208 | 0.71 | FNTA (0.47) | ALDH1A1C3AR1PTAFRCYP1A2CYP3A4 | |
| SCHEMBL6482895 | 0.70 | FNTA (0.47) | ALDH1A1C3AR1PTAFRCYP1A2CYP3A4 | |
| SCHEMBL5394010 | 0.69 | LMNA (0.50) | LMNAALDH1A1PTAFRACHEMEN1 | |
| SCHEMBL83006 | 0.69 | ACHE (0.57) | LMNAPTAFRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7672874 | 0.69 | CHRNA7 (0.57) | LMNAALDH1A1PTAFRCYP1A2CYP3A4 | |
| SCHEMBL6271049 | 0.69 | OPRL1 (0.46) | LMNAALDH1A1C3AR1PTAFRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029861-A1 | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression | KLINGE PHARMA GMBH | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029861-A1 | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression | ALK, IDO1, PDXK | LMNA 3619/4885ALDH1A1 113/4885TBXAS1 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.