Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469483 | 0.85 | MKNK1 (0.46) | PIK3CAATR | |
| SCHEMBL2467819 | 0.80 | KDM4E (0.52) | MAPTPRKDCATR | |
| SCHEMBL2465266 | 0.80 | PIK3CD (0.42) | MAP4K4PIK3CATDP1KMOATR | |
| SCHEMBL2470390 | 0.79 | ATR (0.41) | PLAUEIF4EFTOTDP1KMO | |
| SCHEMBL27520352 | 0.78 | KMO (0.37) | MAP4K4TDP1KMOATR | |
| SCHEMBL2468348 | 0.78 | MAPT (0.54) | KMOMAPT | |
| SCHEMBL11909602 | 0.78 | MAP4K4 (0.50) | MAP4K4PLAUPRKDCATR | |
| SCHEMBL27837915 | 0.77 | KMO (0.54) | EIF4EKMOMAPT | |
| SCHEMBL27504255 | 0.77 | PIN1 (0.51) | EIF4EMAPTPRKDCATR | |
| SCHEMBL27567186 | 0.77 | MAP4K4 (0.45) | MAP4K4PIK3CAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414814-B1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6784137-B2 | SUCH AS 5,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID-N-OXIDE FOR PREEMERGENCE APPLICATION | DOW AGROSCIENCES LLC | 2004-08-31 | — | — | US | disclosed |
| EP-1414814-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2003-06-19 | — | — | US | disclosed |
| WO-2003011853-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | AADAC, DDT, AADAT | MAP4K4 2022/4885PLAU 4746/4885EIF4E 4050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.