Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165973 | 0.79 | ALOX5 (0.60) | ALDH1A1KMT2AALOX5 | |
| Formamide SCHEMBL9729640 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2AMTNR1AALOX5 | |
| SCHEMBL6168726 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KMT2AKDM4EGAAMAPT | |
| SCHEMBL6166743 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KMT2AKDM4EGAAMAPT | |
| SCHEMBL9729866 | 0.71 | ALOX5 (0.63) | MTNR1AALOX5 | |
| SCHEMBL9729495 | 0.69 | ALOX5 (0.61) | MTNR1AALOX5 | |
| SCHEMBL9729814 | 0.68 | ALOX5 (0.65) | MTNR1AALOX5 | |
| Hydrochloric Acid SCHEMBL9729584 | 0.68 | MTNR1A (0.73) | KMT2AKDM4EGAAMAPTMTNR1A | |
| Hydrochloric Acid SCHEMBL9731115 | 0.68 | ALOX5 (0.60) | MTNR1AALOX5 | |
| SCHEMBL2313650 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044974-B1 | N-HYDROXYUREA DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-6291482-B1 | THROMBOXANE SYNTHASE INHIBITORY ANTI-INFLAMMATORY DRUG COMPRISING N-HYDROXY-N-(6-(3-PYRIDYMETHYL)-2H-1-BENZOPYRAN-3-YLMETHYL)URE A; ANTIALLERGIC, ANTIASTHMATIC | NIKKEN CHEMICALS CO., LTD (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1044974-A1 | N-HYDROXYUREA DERIVATIVE AND MEDICINE CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 2000-10-18 | — | — | EP | disclosed |