Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
| ▸ | CIT | O14578 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168939 | 0.89 | TRPV1 (0.44) | PPARGCITPTPN2PTPN1 | |
| SCHEMBL6163974 | 0.87 | MMP12 (0.46) | WNT3AROCK2ROCK1RAB9APKM | |
| SCHEMBL6169697 | 0.85 | ROCK2 (0.40) | PPARGROCK2ROCK1 | |
| SCHEMBL6168382 | 0.84 | WNT3A (0.47) | PPARGWNT3ACIT | |
| SCHEMBL6161506 | 0.82 | PPARG (0.45) | PPARGRAB9A | |
| SCHEMBL6161005 | 0.82 | PPARG (0.45) | PPARGRAB9A | |
| SCHEMBL6160891 | 0.82 | PPARG (0.45) | PPARGRAB9A | |
| SCHEMBL6167624 | 0.82 | HDAC2 (0.42) | CITHDAC4PKM | |
| SCHEMBL10438783 | 0.81 | SMN1; SMN2 (0.48) | RAB9A | |
| SCHEMBL6165947 | 0.78 | TAAR1 (0.49) | PTPN2PTPN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877740-B1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2005-03-30 | — | — | EP | claimed |