Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CIT | O14578 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166677 | 0.89 | PPARG (0.44) | PPARGPTPN2PTPN1CIT | |
| SCHEMBL6167624 | 0.85 | HDAC2 (0.42) | CIT | |
| SCHEMBL6163974 | 0.83 | MMP12 (0.46) | — | |
| SCHEMBL6169634 | 0.83 | MME (0.52) | — | |
| SCHEMBL10438783 | 0.83 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL6169697 | 0.83 | ROCK2 (0.40) | PPARG | |
| SCHEMBL6163339 | 0.81 | ALDH1A1 (0.46) | PPARG | |
| SCHEMBL6162003 | 0.81 | ALDH1A1 (0.46) | PPARG | |
| SCHEMBL6163224 | 0.81 | ALDH1A1 (0.46) | PPARG | |
| SCHEMBL6165947 | 0.80 | TAAR1 (0.49) | PTPN2PTPN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877740-B1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2005-03-30 | — | — | EP | claimed |