Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.32 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 6/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166813 | 0.89 | MIF (0.41) | POLBMAPTHRH2HRH1 | |
| SCHEMBL6167911 | 0.89 | L3MBTL1 (0.37) | P2RY14HRH3CHRM3 | |
| SCHEMBL6166850 | 0.88 | HRH2 (0.35) | MAPTP2RY14HRH3BTKHRH2 | |
| SCHEMBL6168057 | 0.87 | MEN1 (0.41) | TRPC6MEN1KMT2AMAPTTRPC3 | |
| SCHEMBL6168913 | 0.79 | KDM4E (0.41) | — | |
| SCHEMBL6166739 | 0.79 | CHRM2 (0.37) | MEN1KMT2AHRH3CHRM3 | |
| SCHEMBL6166218 | 0.79 | KDM4E (0.36) | MEN1KMT2APOLBMAPTTRPC3 | |
| SCHEMBL6166669 | 0.76 | ABL1 (0.41) | TRPC6MEN1KMT2AABL1BCR | |
| SCHEMBL6166994 | 0.76 | KDM4E (0.46) | — | |
| SCHEMBL6164853 | 0.76 | HTT (0.46) | MEN1KMT2APOLBMAPTHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |